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TABLE OF CONTENTS

Introduction: Every Day that Passes is a Day Brain Cells Vanish:

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Chapter 1: The Brain’s Bermuda Triangle:

What Causes Alzheimer’s and Parkinson’s Disease?

            The Brain’s Bermuda Triangle: Sticky Proteins, Inflammation and Oxidative Stress

Alzheimer’s Disease (AD)

            Inflammation

            Sticky Proteins

            Oxidative Stress

Parkinson’s Disease (PD)

            What’s Going on With Smoking?

Chapter 2: Why Lithium?

The Connection Between Smoking, Lithium and PD

How Could Smoking Cause AD but Prevent PD?

Lithium’s History

Lithium’s Multitude of Neuroprotective Actions

Lithium is Effective in AD and PD Animal Models

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Chapter 3: The Human Evidence        

            Lithium in Drinking Water

Prescription Lithium Use

Lithium, Melanoma and PD Connected by Beta-Catenin and Nurr1

Clinical Trials with Lithium: The “Gold-Standard” Level of Evidence

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Chapter 4:  What’s the hold up?  

            It’s too good to be true

Once a failure always a failure

Lithium’s stigma

The Patent Paradox

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Chapter 5: Biomarkers are the Key.

What are biomarkers and why are they so important?

Lithium’s Effects on AD Biomarkers

PD Clinical Trial Biomarker Results

Follow Your Nose, It Always Knows

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Chapter 6: Should I take over-the-counter lithium supplements?

Lithium is Not FDA-Approved for Treating AD or PD

            Lithium’s Safety Depends on the Dose

            Lithium Orotate or Lithium Aspartate?

What Dose Should I Take?

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Conclusion:

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References: